I have successfully utilized Prolotherapy and trigger point injections for many years using lidocaine and dextrose. I had both of my torn rotator culls treated with Prolo with great results. More recently I had Ozone and lidocaine in both knees giving long term improvements in pain. The procedure was remarkably easy and except for initial injection practically painless.

I recently went to Phoenix to learn the best way to use Ozone from my friend an colleague Nick Meyer DDS. He recently wrote “The Holistic Dental Matrix”

He showed me how to use it and did some injections on me and I taught him how to do a Suprazygomatic Sphenopalatine Ganglion Block.

This morning I decided to try out the Prolozone on myself. I first injected Lidocaine and followed up with injection of Ozone. Remarkable comfortable and little post op pain. I did several areas and there was no pain after, barely even felt like I had done injection. Much more comfortable than lidocaine and dextrose.

Ever the scientist I tried an injection with dextrose and followed by Ozone. More sore than just lidocaine and ozone but not a lot of discomfort.

I recently read “Delayed onset muscle soreness at tendon-bone junction and muscle tissue is associated with facilitated referred pain.” (abstract below) and I did my elbow and and the tendon/ muscle area. More tender than a trigger point but far less painful than prolotherapy on the elbow and 30 minutes later virtually no discomfort similar to the experience with my knees. Previous injection with lido and dextrose was worse but was done when I already had a lot of tenderness.

I am now set up to do Prolozone in my office. I am pretty sure this will give my patients more comfort and better results, but time will tell.

Abstract below:
Exp Brain Res. 2006 Sep;174(2):351-60. Epub 2006 Apr 25.
Delayed onset muscle soreness at tendon-bone junction and muscle tissue is associated with facilitated referred pain.
Gibson W1, Arendt-Nielsen L, Graven-Nielsen T.
Author information
Delayed onset muscle soreness (DOMS) involves central and peripheral pain mechanisms. Referred pain patterns following stimulation of DOMS affected tissue have not been fully described. Referred pain may provide information on how central mechanisms are involved in DOMS, as referred pain is a central mechanism. Further, tendon tissue involvement in DOMS is not clear. This study assessed pressure pain threshold (PPT) sensitivity at the tendon, tendon-bone junction (TBJ) and muscle belly sites of tibialis anterior pre- and during DOMS in 45 subjects (34 males, 11 females). Furthermore, pain and referred pain areas at these three sites in response to hypertonic saline injection (n = 15 per injection site) were investigated pre- and during DOMS. DOMS was induced using controlled plantarflexion from a platform (bodyweight as resistance) causing eccentric contraction of the tibialis anterior muscle. DOMS induced PPT decrease was found at the TBJ and muscle belly sites only (P < 0.001). No mechanical effect was found in the unexercised limb. Maximal pain intensity induced by hypertonic saline given pre-DOMS was significantly higher for the tendon and TBJ injections compared to intramuscular injections (P < 0.05). Significantly higher referred pain frequency and enlarged pain areas were found at the muscle belly and TBJ sites following injection during DOMS compared to pre-DOMS. The results indicate that muscle belly and TBJ sites are sensitised while tendon tissue per se is unaffected by DOMS. Central sensitivity changes caused by DOMS may explain the increase in referred pain frequency and enlarged pain areas. PMID: 16642316 DOI: 10.1007/s00221-006-0466-y