Prolotherapy is used for many musculoskeletal conditions including joint laxity. It can be used to treat varying conditions like rotator cuff injuries, tennis elbow or any joint laxity.

Prolo is short for Proliferation therapy and involves use of an irritant to increase collagen production. Prolotherapy alone cannot treat TMJ disorders but combined with a physiologic orthotic can actually fix some TMJoints.

Physiologic Dentistry is amazing at addressing myofascial components of TMD but does not correct joint laxity.

I frequently utilize prolotherapy in my office for select patients with TMJoint instability.  Prolotherapy can be curative for clicking and popping from loose capsule and ligaments of TM Joint.

In Chicago area Dr Ron Hauser is one of the top prolotherapy experts worldwide. I refer numerous patients to his office for prolotherapy in areas outside the TMJoint. I also refer some of the most severe TM Joint patients for him to do the Prolo because in problem cases he is the number one expert!

I do not know of any other doctors in the midwest who use Prolo therapy for TMJ Disorders. Dr Hauser is now practicing in Oak Park, Illinois and in Frot Meyers, Florida. His PA who has worked with him for years is in Chicago full time and does an excellent job as well.

The following is from Pactical Pain Management Journal. ALL CApitals are my comments.

Dextrose Prolotherapy and Pain of Chronic TMJ Dysfunction
Many of the subjective symptoms of pain, stiffness, and crunching sensation in patients with TMJ dysfunction were reduced greater than 50% in 92% of the prolotherapy patients in this study.

FREQUENTLY
By Ross A. Hauser, MD, Marion A. Hauser, MS, RD and Krista A. Blakemore, BA
According to the American Dental Association, more than 15% of American adults suffer from chronic facial pain.1 One of the most common causes is Tempomandibular Joint Disease (TMD),

A GREAT DEAL OF THEIS PAIN IS ACTUALLY MYOFASCIAL PAIN AND DYSFUNCTION OR TRIGGER POINTS AND TAUT BANDS IN MUSCLE AS WELL AS PAIN FROM FASCIAL ISSUES.

a collective term used to describe a group of medical disorders causing temporomandibular joint (TMJ) pain and dysfunction, and is estimated by The National Institute of Dental and Craniofacial Research of the National Institutes of Health to affect 10.8 million people in the United States at any given time.2 It occurs predominantly in women, with the female to male ratio ranging from 2:1 to 6:1, with 90% of those seeking treatment being women in their childbearing years.3,4

The TMJ is often predisposed to similar degenerative changes and pathologies seen in other synovial joints as a consequence of the frequent and repetitive stresses that the TMJ undergoes.

ALMOST ALL TMJ DISORDERS ARE THE RESULT OF REPETITIVE STRAIN INJURIES AND MICRO TRAUMA OR MACRO TRAUMA LIKE MVA’S.

5 Symptoms commonly associated with TMD include pain at the TMJ, generalized orofacial pain, chronic headaches and earaches jaw dysfunction including hyper- and hypo-mobility and limited movement or locking of the jaw, painful clicking or popping sounds with opening or closing of the mouth (INTERNAL DERANGEMENTS), and difficulty chewing or speaking.6 While pain is the most common symptom, some people report no pain, but still have problems using their jaws. Sometimes the bite just feels “off.” Additional symptoms may include ringing in the ears, ear pain, decreased hearing, dizziness, and vision problems.7

MANY CHRONIC HEADACHES TREATED AS MIGRAINES, CLUSTERS, AUTONOMIC CEPHALGIAS, TENSION HEADACHES, FACIAL PAIN, HEMIPLEGIC MIGRAINES ETC ARE IN FACT REFERRED MUSCLE HEADACHES AND ASSOCIATED WITH TMJ AND MPD. CORRECTION OF ORTHOPEDIC ISSUES CAN OFTEN ELIMINATE THEM WITHOUT MEDICATION.

The first-line approach to managing TMD typically includes resting the jaw, relaxing the jaw muscles, and doing jaw exercises as recommended by a physical therapist.
A NEUROMUSCULAR DENTIST TRAINED IN DIAGNOSING THESE ISSUES CAN BEST DETERMINE WHICH ARE MOST IMPORTANT ISSUES.
Recommendations may also include eating a soft diet that minimizes hard repetitive chewing of crunchy or chewy foods, such as bagels and steak. All gum chewing must be stopped, talking minimized, and teeth clenching discouraged. Relaxation exercises that emphasize gentle range of motion of the joint are recommended. Application of warm compresses to the affected area twice daily, for 10 minutes, to decrease pain and increase joint movement are done. If this fails, then typically a short course of an anti-inflammatory medication such as ibuprofen is prescribed and often a dental consultation is given. The dentist then evaluates the patient for malocclusion and bruxism. Many times, a mouth splint used at night can completely resolve or control the problem.
A NIGHT-TIME APPLIANCE IS USUALLY INDICATED IF PAIN IS ONLY AT NIGHT OR FIRST THING IN THE MORNING. DAYTIME PAIN IS BEST APPROACHED WITH 24/7 ORTHOTIC. NEUROMUSCULAR DENTISTRY UTILIZES A 24 HOUR ORTHOTIC WHICH USUALLY GIVES THE BEST RESULTS.

When pain, clicking, and locking symptoms persist, TMD sufferers commonly seek out the advice of a myriad of TMJ dental and surgical specialists. Because the causes of TMD are varied and run the gamut from mechanical issues—such as disc degeneration and dislocation or erosion of the fibrocartilagenous surfaces of the condyle, fossa and articular eminence—to hormonal as well as psychological causes,9,10,11 the treatment approaches for the chronic TMJ case are also quite varied. As surgery is considered a last resort for TMD, it is common for sufferers to seek out alternatives and one of the treatments they may consider is prolotherapy.
NEUROMUSCULAR DENTISTS ESPECIALLY REALIZE THE IMPORTANCE OF THE MUSCULAR AND FASCIAL TISSUES.

This article presents a retrospective analysis of patients who received dextrose prolotherapy to their tempomandibular joints, and was conducted on a patient population from a charity clinic in rural Illinois. Patients were called by an independent data collector and asked numerous questions concerning their response to the dextrose prolotherapy they received. The data was analyzed in all TMJ pain patients, as well as a subset whose medical doctors told them there were no other treatment options for their TMJ dysfunction and pain.
DEXTROSE PROLOTHERAPY IS WHAT I ROUTINELY UTILIZE IN MY OFFICE, WHEN I REFER PATIENTS TO DR HAUSSER HE WILL UTILIZE DEXTROSE AND OTHER MODALITIES.

Prolotherapy Modality
Prolotherapy, as defined by Webster’s Third New International Dictionary, is “the rehabilitation of an incompetent structure, such as a ligament or tendon, by the induced proliferatin of cells.” “Prolo” comes from the world proliferate. Prolotherapy injections proliferate or stimulate the growth of new, normal ligament and tendon tissue.12 In human studies on prolotherapy, biopsies performed after the completion of treatment showed statistically significant increases in collagen fiber and ligament diameter of up to 60%.13

I LIKE TO THINK OF PROLOTHERAPY AS REGROWING WORN OUT PARTS.

Prolotherapy is based on the concept that the cause of most chronic musculoskeletal pain is ligament and/or tendon weakness (or laxity). NEUROMUSCULAR DENTISTRY AGREES BUT FEELS THE CAUSE OF THE TENDON OR LIGAMENT WEAKNESS IS SECONDARY TO MISUSE OR CHRONIC REPETITIVE STRAIN INJURIES AND THAT CORRECTING UNDERLYING ISSUES IS ESSENTIAL FOR THE BEST RESULTS.
PROLOTHERAPY IMPROVES PROGNOSIS AND OUTCOMES COMPARED TO TMJ TREATMENT ALONE.

Prolotherapy has been shown in one double-blinded animal study over a six-week period to increase ligament mass by 44%, ligament thickness by 27%, and the ligament-bone junction strength by 28%.14 Another animal study confirmed that prolotherapy induced the normal healing reaction that occurs when an injured tissue is healing itself. In this study, the prolotherapy caused the circumference of tendons to increase by approximately 25% after six weeks time.15 I HAVE FOUND IN MY PRACTICE VERY LITTLE NOTABLRE CHANGE ONTHER THAN REDUCTION IN PAIN AND LOOSE LIGAMENTS OF THE JOINT.

HISTORY OF PROLOTHERAPY:
Prolotherapists have a long history treating TMD since the time of Louis W. Schultz, MD, DDS in the 1930’s. Dr. Schultz was unique in that he was both a dentist and a medical doctor. He was an Associate Professor in the Department of Surgery at the University of Illinois and Rush College of Medicine. He published several papers on the treatment of subluxation of the temporomandibular joint, including one in 1937 in the Journal of the American Medical Association.16 In this paper he described just how common TMJ syndrome was and that the traditional treatments of rest, appliances in the mouth, physical therapy, and surgery were only partially successful. He described a simple method of shortening and strengthening the TMJ capsule by injection (later termed prolotherapy). He tested various solutions in animals until he found one that caused a strengthening of the ligaments that support the TMJ but caused no injury to other structures.17 In regard to prolotherapy into the TMJ he found that:

There was no alteration of the normal joint cavity; the proliferation occurred in the ligaments.
There were no gross changes in the ligaments other than their thickening.
Lymphocytes infiltrate the area injected within 30 minutes.
Proliferation of tissue can be seen in four to six days.
He found that a series of three to five injections were required to often permanently stop the clicking, pain, and hypermobility of the TMJ joint. Dr. Schultz noted that over the course of his twenty years of doing prolotherapy for TMD, not only was it effective, but the treatment lacked significant side effects.

Dr. Schultz taught the technique of TMJ prolotherapy to Gustav S. Hemwall, MD. The primary author has worked with Dr. Hemwall and eventually assumed his practice upon his retirement from medicine in 1996. After acquiring Dr. Hemwall’s practice, Dr. Schultz’s son came to the clinic for a prolotherapy evaluation. He commented that in his father’s many years of practice as a dentist, medical doctor, and surgeon, the procedure that gave him the most amount of satisfaction in treating a TMJ case was prolotherapy.

I CERTAINLY UNDERSTAND THAT SENTIMENT. I HAVE BEEN UTILIZING PROLOTHERAPY FOR WELL OVER 30 YEARS AND HAVE ALWAYS FOUND IT TO BE VERY EFFECTIVE. IT CAN OFTEN BE THE KEY TO CURING RATHER THAN JUST TREATING THE TM JOINTS (TMJ)

THE FOLLOWING REFERENCES ARE FROM THE ARTICLE BUT I SUGGEST READING THIS ARTICLE FROM THE NHLBI OF THE NIH TO BETTER UNDERSTAND THE FULL SCOPE OF TMJ ISSUES.
CARDIOVASCULAR AND SLEEP-RELATED CONSEQUENCES OF TEMPOROMANDIBULAR DISORDERS (LINK BELOW)
https://www.nhlbi.nih.gov/files/docs/workshops/tmj_wksp.pdf

THIS ARTICLE BY SHIMSHAK EXPLAINS HOW IMPORTANT TMJ IS RELATED TO OVERALL HEALTH EXPENDITURES.
Cranio. 1998 Jul;16(3):185-93.
Health care utilization by patients with temporomandibular joint disorders.

Shimshak DG1, DeFuria MC.
Author information
Abstract
The claims data base of a large New England managed care organization was used to compare the health care utilization patterns of patients with TMJ disorders to non-TMJ subjects. Inpatient, outpatient and psychiatric claims data were examined over a wide range of diagnostic categories. Age and sex adjusted results showed that, overall, patients with TMJ disorders were greater utilizers of health care services and had higher associated costs than non-TMJ subjects. For some of the major diagnostic categories, such as nervous, respiratory, circulatory, and digestive, the inpatient and outpatient claims differences in utilization and costs were as large as 3 to 1. For only one diagnostic category, pregnancy and childbirth, were utilization and costs greater for non-TMJ subjects than TMJ patients. The psychiatric claims for TMJ patients exhibited differences that were at least twice as large as those for the non-TMJ subjects.
PMID: 9852811
[Indexed for MEDLINE]

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